The Connectomic Revolution

An even more recent and exciting revolution happening now is this connectomic revolution, where we’re able to map in exquisite detail the connections of a part of the brain, and soon even an entire insect brain. It’s giving us absolute answers to questions that we would have debated even just a few years ago; for example, does the insect brain work as an integrated system? And because we now have a draft of a connectome for the full insect brain, we can absolutely answer that question. That completely changes not just the questions that we’re asking, but our capacity to answer questions. There’s a whole new generation of questions that become accessible.

When I say a connectome, what I mean is an absolute map of the neural connections in a brain. That’s not a trivial problem. It's okay at one level to, for example with a light microscope, get a sense of the structure of neurons, to reconstruct some neurons and see where they go, but knowing which neurons connect with other neurons requires another level of detail. You need electron microscopy to look at the synapses.

ANDREW BARRON is the Australian Research Council Future Fellow and Deputy Head of the Department of Biological Sciences at Macquarie University. He is a neuroethologist with a particular focus on studying the neural mechanisms of honey bees. Andrew Barron's Edge Bio Page