There's a notorious problem with defining information within physics, namely that on the one hand information is purely abstract, and the original theory of computation as developed by Alan Turing and others regarded computers and the information they manipulate purely abstractly as mathematical objects. Many mathematicians to this day don't realize that information is physical and that there is no such thing as an abstract computer. Only a physical object can compute things.
I think it's important to regard science not as an enterprise for the purpose of making predictions, but as an enterprise for the purpose of discovering what the world is really like, what is really there, how it behaves and why.
DAVID DEUTSCH is a Physicist at the University of Oxford. His research in quantum physics has been influential and highly acclaimed. He is the author of The Beginning of Infinity and The Fabric of Reality. David Deutsch's Edge Bio Page