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Home > Soul of a Molecular Machine

Video : LIFE

Soul of a Molecular Machine

We're at the threshold of a new age of structural biology, where these things that everybody thought were too difficult and would take decades and decades, are all cracking. Now, we're coming to pieces of the cell. The real advance is that you're going to be able to look at all these machines and large molecular complexes inside the cell. It will tell you detailed molecular organization of the cell. That's going to be a big leap, to go from molecules to cells and how cells work.

In almost every disease, there's a fundamental process that's causing the disease, either a breakdown of a process, or a hijacking of a process, or a deregulation of a process. Understanding these processes in the cell in molecular terms will give us all kinds of ways to treat disease. They'll give us new targets for drugs. They'll give us genetic understanding. The impact on medicine is going to be quite profound over the long-term.

VENKATRAMAN "VENKI" RAMAKRISHNAN is an Indian-born American and British structural biologist. He shared the 2009 Nobel Prize in Chemistry with Ada Yonath and Tom Steitz and is the current President of the Royal Society. His many scientific contributions include his work on the atomic structure of the ribosome. Venki Ramakrishnan's Edge Bio Page

Soul of a Molecular Machine [1]

We're at the threshold of a new age of structural biology, where these things that everybody thought were too difficult and would take decades and decades, are all cracking. Now, we're coming to pieces of the cell. The real advance is that you're going to be able to look at all these machines and large molecular complexes inside the cell. It will tell you detailed molecular organization of the cell. That's going to be a big leap, to go from molecules to cells and how cells work.

In almost every disease, there's a fundamental process that's causing the disease, either a breakdown of a process, or a hijacking of a process, or a deregulation of a process. Understanding these processes in the cell in molecular terms will give us all kinds of ways to treat disease. They'll give us new targets for drugs. They'll give us genetic understanding. The impact on medicine is going to be quite profound over the long-term.

VENKATRAMAN "VENKI" RAMAKRISHNAN is an Indian-born American and British structural biologist. He shared the 2009 Nobel Prize in Chemistry with Ada Yonath and Tom Steitz and is the current President of the Royal Society. His many scientific contributions include his work on the atomic structure of the ribosome. Venki Ramakrishnan's Edge Bio Page [2]

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Links:
[1] https://www.edge.org/video/soul-of-a-molecular-machine
[2] https://www.edge.org/memberbio/venki_ramakrishnan