...This year, in advance of President Obama's speech, we're looking at the difficult questions the president will likely ignore on Tuesday. In 2013, what should weigh on American minds?

That's the question posed by Edge.org in 2013. Every year, Edge poses a question to a group of experts from a variety of fields, and judging from this year's responses, Americans have plenty of concerns.

Dr. P. Murali Doraiswamy, professor of psychiatry at Duke University, worries that American mental health diagnoses are blindly exported abroad. Lisa Randall, professor of physics at Harvard University and author of "Warped Passages: Unraveling the Mysteries of the Universe's Hidden Dimensions," worries about the waning investment in research and development.