To arrive at the edge of the world's knowledge, seek out the most complex and sophisticated minds,
put them in a room together, and have them ask each other the questions they are asking themselves.
Links:
[1] http://www.edge.org/news/world-news-tonight
[2] http://tinyurl.com/d8yf9fx
[3] http://www.edge.org/annual-question/what-questions-are-you-asking-yourself
[4] http://www.edge.org/documents/Invention.html